<div dir="ltr">Hi All,<div><br></div><div>I'm sending this invite out on behalf of Nina's Idealab journal club who will be leading the journal club with Derek tonight to discuss Gene editing technology, please feel free to join and also sign up for the free virtual meet up! </div>
<div><br></div><div>Gene editing technology ROCKS :)</div><div><br></div><div><a href="http://www.meetup.com/Berkeley-Biolabs/events/136129042/">http://www.meetup.com/Berkeley-Biolabs/events/136129042/</a><br></div><div><br>
</div><div><p style="margin:0px 0px 0.7em;padding:0px;font-family:verdana,arial,sans-serif;font-size:13.63636302947998px;color:rgb(85,85,85);line-height:17.27272605895996px;background-color:rgb(230,230,230)">The next global Biojournal club is this Thursday, Aug 22nd at 5:30pm PST.  The session will be held via <a href="http://zoom.us/" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">zoom.us</a><span style="font-family:inherit">.  If you are interested in participating, please make a </span><a href="http://zoom.us/" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">zoom.us</a> <span style="font-family:inherit">account if you have not done so already.</span></p>
<p style="margin:0px 0px 0.7em;padding:0px;font-family:verdana,arial,sans-serif;font-size:13.63636302947998px;color:rgb(85,85,85);line-height:17.27272605895996px;background-color:rgb(230,230,230)"></p><p style="margin:0px 0px 0.7em;padding:0px;font-family:verdana,arial,sans-serif;font-size:13.63636302947998px;color:rgb(85,85,85);line-height:17.27272605895996px;background-color:rgb(230,230,230)">
<span style="font-family:inherit">We can also send you 2 short papers on CRISPR applications. Derek Jacoby will discuss one of them, and Nina will go through the other. </span></p><p style="margin:0px 0px 0.7em;padding:0px;font-family:verdana,arial,sans-serif;font-size:13.63636302947998px;color:rgb(85,85,85);line-height:17.27272605895996px;background-color:rgb(230,230,230)">
</p><p style="margin:0px 0px 0.7em;padding:0px;font-family:verdana,arial,sans-serif;font-size:13.63636302947998px;color:rgb(85,85,85);line-height:17.27272605895996px;background-color:rgb(230,230,230)">Nina DiPrimo, PostDoc at UC Berkeley, Biocoder Journal editor and Berkeley Biolabs Founding Partner will be leading the discussion and will be the primary contact if you have any questions.</p>
<p style="margin:0px 0px 0.7em;padding:0px;font-family:verdana,arial,sans-serif;font-size:13.63636302947998px;color:rgb(85,85,85);line-height:17.27272605895996px;background-color:rgb(230,230,230)">More info on CRISPR's from Wikipedia:</p>
<p style="margin:0px 0px 0.7em;padding:0px;font-family:verdana,arial,sans-serif;font-size:13.63636302947998px;color:rgb(85,85,85);line-height:17.27272605895996px;background-color:rgb(230,230,230)"><b>CRISPRs</b> (<b>C</b>lustered <b>R</b>egularly <b>I</b>nterspaced <b>S</b>hort<b>P</b>alindromic <b>R</b>epeats) are <a href="http://en.wikipedia.org/wiki/Locus_(genetics)" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">loci</a> containing multiple short direct repeats that are found in the genomes of approximately 40% of sequenced <a href="http://en.wikipedia.org/wiki/Bacteria" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">bacteria</a> and 90% of sequenced <a href="http://en.wikipedia.org/wiki/Archaea" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">archaea</a>. CRISPR functions as a prokaryotic immune system, in that it confers resistance to exogenous genetic elements such as<a href="http://en.wikipedia.org/wiki/Plasmids" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">plasmids</a> and <a href="http://en.wikipedia.org/wiki/Phage" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">phages</a>.The CRISPR system provides a form of <a href="http://en.wikipedia.org/wiki/Acquired_immunity" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">acquired immunity</a>. Short segments of foreign DNA, called spacers, are incorporated into the genome between CRISPR repeats, and serve as a 'memory' of past exposures. CRISPR spacers are then used to recognize and silence exogenous genetic elements in a manner analogous to <a href="http://en.wikipedia.org/wiki/RNAi" style="display:inline;font-family:inherit;color:rgb(42,155,199);text-decoration:none">RNAi</a> in eukaryotic organisms.</p>
</div><div><br clear="all"><div><br></div>-- <br><div dir="ltr">Ryan Bethencourt<br><br><span>Tel: <span id="gc-number-0" class="" title="Call with Google Voice">(415) 825 2705</span></span><div><span>Conf Call: <span id="gc-number-1" class="" title="Call with Google Voice">(650) 741 5013</span></span><br>
<a href="mailto:ryan.bethencourt@gmail.com" target="_blank">ryan.bethencourt@gmail.com</a><br><br><a href="http://www.litmususa.com/" target="_blank">http://www.litmususa.com/</a></div><div><a href="http://berkeleybiolabs.com/" target="_blank">http://berkeleybiolabs.com/</a></div>
<div><br><a href="http://www.bamh1.com" target="_blank">www.bamh1.com</a><br><a href="http://www.linkedin.com/in/bethencourt" target="_blank">www.linkedin.com/in/bethencourt</a><br><a href="http://www.logos-press.com/books/biotechnology_business_development.php" target="_blank">www.logos-press.com/books/biotechnology_business_development.php</a><br>
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