[sudo-discuss] 2019-nCoV is a synthetic hybrid of SARS and AIDS

[Nick Mapsy]

Possible, I guess? But extraordinary claims demand extraordinary evidence.
Glancing at the figures, I see a handful of amino acids that coincide. I'm
not enough of a virologist to know how likely that is to happen by chance
(or convergent evolution). I'll wait until I see something at least
peer-reviewed.

Nick

On Mon, Feb 3, 2020 at 9:12 PM Jake <jake at spaz.org> wrote:

> I'm sure this is unrelated but I guess China built their first BSL4 lab a
> year
> ago...in Whuan.
>
>
> http://english.www.gov.cn/state_council/ministries/2018/01/04/content_281476001535134.htm?fbclid=IwAR3zi1K6nUpgiMvePhmDNatta66nt2QJSXg6KZUlUyOLZSC_pLA2j35JLtE
>
>
> On Mon, 3 Feb 2020, Jake wrote:
>
> > We then translated the aligned genome and found that these inserts are
> > present
> > in all Wuhan 2019-nCoV viruses except the 2019-nCoV virus of Bat as a
> host
> > [Fig.S4]. Intrigued by the 4 highly conserved inserts unique to
> 2019-nCoV we
> > wanted to understand their origin. For this purpose, we used the
> 2019-nCoV
> > local alignment with each insert as query against all virus genomes and
> > considered hits with 100% sequence coverage.
> >
> > Surprisingly, each of the four inserts aligned with short segments of
> the
> > Human
> > Immunodeficiency Virus-1 (HIV-1) proteins. The amino acid positions of
> the
> > inserts in 2019-nCoV and the corresponding residues in HIV-1 gp120 and
> HIV-1
> > Gag are shown in Table 1. The first 3 inserts (insert 1,2 and 3) aligned
> to
> > short segments of amino acid residues in HIV-1 gp120. The insert 4
> aligned to
> > HIV-1 Gag. The insert 1 (6 amino acid residues) and insert 2 (6 amino
> acid
> > residues) in the spike glycoprotein of 2019-nCoV are 100% identical to
> the
> > residues mapped to HIV-1 gp120. The insert 3 (12 amino acid residues) in
> > 2019-
> > nCoV maps to HIV-1 gp120 with gaps [see Table 1]. The insert 4 (8 amino
> acid
> > residues) maps to HIV-1 Gag with gaps.
> >
> > Although, the 4 inserts represent discontiguous short stretches of amino
> > acids
> > in spike glycoprotein of 2019-nCoV, the fact that all three of them
> share
> > amino
> > acid identity or similarity with HIV-1 gp120 and HIV-1 Gag (among all
> > annotated
> > virus proteins) suggests that this is not a random fortuitous finding.
> In
> > other
> > words, one may sporadically expect a fortuitous match for a stretch of
> 6-12
> > contiguous amino acid residues in an unrelated protein.  However, it is
> > unlikely that all 4 inserts in the 2019-nCoV spike glycoprotein
> fortuitously
> > match with 2 key structural proteins of an unrelated virus (HIV-1).
> >
> > https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full.pdf
> >
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