Phage therapy

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The isolation, characterization and pre-clinical screening of novel bacteriophages as therapies for antibiotic resistant, sexually-transmitted bacterial infections.

Next Call: 1/20/12 8:00pm PST/10:00pm CST (meeting notes available here.)

Discussion Topics Include:

  • Introduction into the project
  • Discussion of organizational (non-hierarchical) structure
  • Introduction to molecular genetics of Phage (lytic vs. lysogenic)
* Lytic phage kill; Lysogenic incorporate in host genome then wait for opportunity to become lytic!
* Lysogenic phage are induced (UV light, chemicals) and prophage DNA is excised, phage are created, bacteria lyse!
  • Methods of Phage Isolation and Characterization
*"Isolation and Characterization of Bacteriophages for Neisseria" L.N. Phelps, J. gen. Virol (1967) 1, 529-532.
  • Molecular Manipulation of Phage
  • Molecular Biology and Immunology of target organisms.

if you'd like to attend the conference call, please contact: Craig (craigrouskey [at] riseup [dot] net)


Here are some videos to review