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:b. Provide in-the-lab training and experience for those with the desire to pursue citizen science. | :b. Provide in-the-lab training and experience for those with the desire to pursue citizen science. | ||
== Anticipated | == Anticipated Challenges to Our Approach == | ||
#rapid clearance of phages by human host and bacteria: bacterial strain resistance / anti-phage antibodies. | |||
#patient safety: altering phage to prevent lysis of gram negative species. | |||
#rapid clearance of phages | #bacterium targeting and optimization: altering the binding kinetics of Phage adherence. | ||
#patient safety | |||
#bacterium targeting and optimization | |||
#narrow range of hosts | #narrow range of hosts | ||
#phage purity | #achieving phage purity: while administering directly may be hazardous if bacteria is not removed. | ||
#poor stability of phage | #poor stability of phage: how do we preserve phage ex vivo and ensure that is viable upon administration? | ||
# | #Addressing previous citizen science failures and conducting research with a greater adherence to quality. | ||
# | #Preventing Lysogeny. | ||
== Experiments == | == Experiments == |
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